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Nayan Patel: is worse than the religion and politics

Choi, E

Those patients will continue to access the drug through traditional coverage

Copper is a required cofactor for lysyl oxidase, the enzyme that cross-links collagen and elastin which offers a route by which a copper carrier could affect matrix quality

This risk is heightened by genetic variants such as the OATP1B1 R57Q polymorphism, which impairs drug transport and can lead to systemic toxicity (62, 63)