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Contraindications Absolute contraindications include Wilsons Disease or other copper metabolism disorders, known copper allergy or hypersensitivity, and pregnancy or breastfeeding (no safety data exists for systemic use during these periods)

Targeted disruption of the type 1 selenodeiodinase gene (Dio1) results in marked changes in thyroid hormone economy in mice

Cerenkov luminescence imaging (CLI) for image-guided cancer surgery

17,47,57,61,62,63 The effects are mediated through altered transcription of numerous genes that are associated with various aspects of cancer progression

However, it's important to set realistic expectations

All safety data extrapolates from individual peptide studies conducted primarily in animals