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A 2015 rabbit osteoarthritis model found that intra-articular injection of AOD-9604, particularly combined with hyaluronic acid, improved cartilage integrity and reduced joint degradation

Specific concerns include: Cardiovascular risk: High intake of saturated fat may adversely affect lipid profiles in some individuals, with marked rises in LDL cholesterol and apolipoprotein B observed in certain cases Kidney function: The high protein load may stress kidneys in those with pre-existing renal impairment

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Gauderer MW, Crane MM, Green JA, et al