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doi: 10.1038/nm.3291 138 LiuYSongYLinDLeiLMeiYJinZet al

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This specialized form of GR is encoded by the same gene as cytosolic GR but contains a mitochondrial targeting sequence that directs it to this organelle

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GHK-Cu enhances wound healing through multiple mechanisms including stimulation of angiogenesis (essential for delivering nutrients and oxygen to healing tissue), enhancement of collagen and glycosaminoglycan synthesis (providing structural matrix for tissue reconstruction), and modulation of inflammatory responses (preventing chronic inflammation while supporting protective immune functions)

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[DOI] [PubMed] [Google Scholar] 19.Oppenheimer L, Wellner VP, Griffith OW, Meister A

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Gastroenterology 127 , 17041713 (2004)

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